discovered that miR-181a-5p inhibits pyroptosis through the downregulation of NEK7 in lipopolysaccharide (LPS)-induced HK-2 cells and cecum ligation and puncture (CLP)-induced mice and indicated that miR-181a-5p is a new potential therapeutic target for sepsis-induced AKI therapy (130). The gene discussed is NEK7; the disease is acute kidney injury.