On the broad antigen level, fold change difference for HLA-A (1, 2, 3, 9, 10, 11, 19, 28, 36 80) expression comparing T1D islet recipients and pancreas donors ranged between 0.5 (HLA-A11) to 1.4 (HLA-A1); for HLA-B (5, 7, 8, 12, 13, 14, 15, 16, 17, 18, 21, 22, 27, 35, 37, 40, 41, 42, 46, 47, 48, 53, 59, 67, 70, 73, 78, 81, 82) between 0.4 (HLA-B37, HLA-B17) to 2.2 (HLA-B8); for HLA-DR (1, 2, 3, 4, 5, 6, 7, 8, 9, 10) between 0.1 (HLA-DR10) to 2.6 (HLA-DR3). Here, HLA-A is linked to type 1 diabetes mellitus.