INS and Hypoinsulinemia: In addition, the PPR values in the PPD subgroup of hypoinsulinemia after insulin addition did not differ significantly from those measured in the control of normoinsulinemia (p > 0.05; two-way ANOVA), while control PPR values in normoinsulinemia and in the PPD subgroup of hypoinsulinemia significantly differed (p < 0.05; two-way ANOVA).