GO analysis revealed that predictive genes are primarily enriched in the Wnt signaling pathway, MAPK cascade, regulation of apoptotic signaling pathway, base excision repair gap filling, positive regulation of T cell apoptotic process, etc. KEGG pathway revealed systemic lupus erythematosus, linoleic acid metabolism, regulation of autophagy, Notch signaling pathway, MAPK signaling pathway, Wnt signaling pathway, apoptosis, ERBB signaling pathway, and mTOR signaling pathway were correlated with the seven prognostic genes. Here, MTOR is linked to systemic lupus erythematosus.