PI3K/AKT/mTOR, Wnt/β-catenin, TGF-β, p53, FAK/PI3K/AKT/GSK3β/Snail, STAT3, FAK/AKT/β catenin, Ras/ERK, NF-κB and FOXO signaling pathways are among signaling pathways that are modulated by lncRNAs in the context of prostate cancer. The gene discussed is PTK2; the disease is Familial prostate cancer.