Not only that, they also found that renal CSCs were positive for C-X-C motif chemokine receptor 4 (CXCR4), mesenchymal-epithelial transition factor (MET) and homing cell adhesion molecule (CD44), which accounted for an average of 2.2% of the total tumor cells (133). This evidence concerns the gene CXCR4 and neoplasm.