MET and non-small cell lung carcinoma: Table 3 shows the definition/cut-off value of the different MET aberrations. Our results indicate that NGS may serve as an alternative method for detecting MET amplification or polysomy in NSCLC tissues. Liquid biopsy could serve as a substitute for tissue biopsy for detecting MET amplification using NGS. It appears that polysomy does not act as a true oncogenic driver, even though it has a high MET copy number.