CYLD and neuroblastoma: We also compared our 15-gene model to those proposed in previous studies: The first one is a three-gene model, including CKB, DST, and DUT; and the second one is a six-gene model, including CYLD, JAK1, APC, ERH, CNBP, and BAX. In our used NB cohort dataset, we didn’t find the expression of DST and APC. Therefore, we compared our 15-gene model to the two-gene model (CKB, and DUT) and the five-gene model (CYLD, JAK1, ERH, CNBP, and BAX).