The specific genetic variants associated with the outcome of NB patients include amplification of MYCN (13), DDX1 (14), NAG (15), and ALX (16), and mutations in genes CASC15, BARD1, CHEK2, LMO1, LIN28B, AXIN2, BRCA1, TP53, SMARCA4, and CDK1NB (17). This evidence concerns the gene MYCN and neuroblastoma.