There were no statistically significant differences in the following demographic and clinical parameters among the three groups: sex, age at biopsy, duration, the proportion of patients with hypertension, the proportion of patients with NS, serum album, eGFR, serum IgM, serum C3, serum C4, the proportion of patients with hematuria, and daily urinary protein. The gene discussed is C4A; the disease is hypertensive disorder.