BTG3 and systemic lupus erythematosus: The subsequent 1982 Revised Criteria for the Classification of SLE, and its update, the 1997 American College of Rheumatology (ACR) Criteria, incorporated non-obligatory immunological criteria, such as the presence of an ANA, anti-DNA, anti-Smith or antiphospholipid antibodies, which may have contributed to its higher sensitivity and specificity than the 1971 classification criteria (5).