In addition, functional experimental studies showed that HJURP acts as a tumor driver, promoting proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT) and inhibiting apoptosis in HCC cells (Yi, 2015; Hu et al., 2017; Chen et al., 2018; Chen T. et al., 2019). This evidence concerns the gene HJURP and hepatocellular carcinoma.