The comparison of clinicopathological factors showed significant differences in the total number of SLN, number of negative SLN, ratio of SLN macrometastases, TS, LVI, pathological type and tumor site between the nSLN-positive and nSLN-negative patients (P < 0.05), while the difference between the two groups in age, BMI, NLR, histological grade, molecular type, ER status, PR status, Ki-67 index, HER2 status, multifocal lesions, menstrual status, and family history of malignancy was not significant (Table 1). Here, ESR1 is linked to neoplasm.