Furthermore, in human ICC, patients with a higher proportion of CD103+CD8+T cells lived longer than patients with a lower proportion of CD103+CD8+T cells (P = 0.0582, HR = 0.542, 95% CI: 0.258–1.142, Fig. 3C), and patients with a higher ratio of CD103+CD8+T cells over total CD8+T cells displayed a better OS than those with a lower ratio of CD103+CD8+T cells over total CD8+T cells (P = 0.1091, HR = 0.472, 95% CI: 0.224–0.994, Fig. 3B). Here, CD8A is linked to intrahepatic cholangiocarcinoma.