The percentage of infiltrating CD103+ immune cells in human HCC tissues was significantly higher compared with the adjacent normal tissues (P = 0.0307, Supplementary Fig. 1B), while no difference was found about the percentage of infiltrating tissue-resident CD103+CD8+T cells (P = 0.681, Supplementary Fig. 1C). The gene discussed is ITGAE; the disease is hepatocellular carcinoma.