The literature [22] reports that a low CD4 + T-cell count was a high-risk factor affecting the prognosis of patients with AIDS combined with CM, and the CD4 + T-lymphocyte count of the 32 patients in Group A was less than 100 cells/μl, accounting for 93.8%, which is consistent with clinical reports. The gene discussed is CD4; the disease is cutaneous mastocytosis.