Noteworthily, despite the fact that plasma FCGR3A and haptoglobin can discriminate MIAC/IAI from non-MIAC/IAI among a cohort of women with PPROM with similar diagnostic accuracy to serum CRP (a prototype marker of inflammation tested in the blood), their diagnostic performance is poor to fair (AUC: 0.59–0.65; Table 4). Here, HP is linked to preterm premature rupture of the membranes.