PERK and CHOP are implicated in the regulation of Th17 inflammatory cytokines, and one study specifically found that inhibiting PERK inhibits Th17 cell differentiation55,56 Targeting the PERK-eIF2α pathway has been reported as an ideal strategy for protecting oligodendrocyte protection in MS, and we show for the first time that GA may be able to57. The gene discussed is EIF2AK3; the disease is myeloid sarcoma.