Since IGF2BP1 was reported to act as a reader for m6A, the most prevalent modification in eukaryotic RNAs, and promote the stability of m6A-modified transcripts27,28, we sought to identify its downstream effectors that mediate OXA resistance in HCC by using MeRIP (m6A)-sequencing and RIP sequencing. Here, IGF2BP1 is linked to hepatocellular carcinoma.