Among all drug classes, SGLT-2 inhibitors, GLP-1 receptor agonists, and finerenone show benefits in reducing all cause mortality, admission to hospital due to heart failure (SGLT-2 inhibitors and—probably—finerenone are the most effective drug treatments), and end stage kidney disease (SGLT-2 inhibitors are the most effective drug treatments). Here, GLP1R is linked to heart failure.