The MFI of circulating CD197 labeled monocytes decreased on average 6.3-fold compared to pre-treatment baseline levels with a 1.26-fold increase (p< 0.01) in the MFI of SCD bound CD197 labeled monocytes; whereas the MFI of circulating CD192 labeled monocytes increased after 3 days of treatment compared to baseline and prior levels on days 1–3 (p<0.002). The gene discussed is CCR7; the disease is Schnyder corneal dystrophy.