SCG2 and brain injury: Based on previous literature reporting increases in secretoneurin concentrations in association with adult brain injury [11, 12], and particularly in full-term neonates suffering from perinatal asphyxia with hypoxic-ischaemic brain injury [13], we hypothesized that secretoneurin might also be increased in very preterm infants with cerebral imaging pathology, but detected no significant differences between infants with apparent brain injury and those without on ultrasound or magnetic resonance imaging.