In an study carried out with a Lewis lung carcinoma 3LL cell line and B16 melanoma cell line, heat-stressed tumour cells (HS-TEX) contained CL2, CCL3, CCL4, CCL5 and CCL20 chemokines and were able to attract CD11c( +) DC, CD4( +) and CD8( +) T cells. Here, CD4 is linked to neoplasm.