ISOC2 and craniosynostosis: However, also in this case interesting examples of co-occurrences may be found, often involving genes known to be associated with Psoriasis, such as QTRT1 (Baurecht et al. 2015), as well as genes related to other diseases, e.g. ERF, implied in complex craniosynostosis (Twigg et al. 2013), and ISOC2, biomarker of Osteoarthrosis Deformans (Ruiz-Romero et al. 2009).