SYTL2 and neoplasm: Besides, we further divided epithelial cells into three common subpopulations: basal cells (KRT14+, KRT5+), luminal 1 cells (SPLI+, PROM1+), and luminal 2 cells (ANKRD30A+, SYTL2+) (Figure S3),23 and found that Scissor+ tumor cells could be distributed in all three subpopulations, particularly the highest proportion of luminal 1 cells and the lowest proportion of basal cells (Figure 2C).