Interestingly, our results showed that many JAK‐STATs signaling as well as MHC components related molecules such as IRF1, HLA‐F, HLA‐DRB5, HLA‐DRB1, HLA‐DPB1, and HLA‐DMA can promote the survival of breast cancer patients24, 25, 26, 27, 28 (Figure 3E). This evidence concerns the gene HLA-C and breast cancer.