Herein, we further performed a transcriptome‐wide gene set activity analysis of 50 hallmarks of cancer, and found that these significantly activated hallmarks in Scissor+ tumor cells included “fatty acid metabolism,” “MTORC1 signaling,” “PI3K AKT signaling,” and “MYC target,” etc. (Figure 3A), which are usually promoting tumor progression. This evidence concerns the gene AKT1 and neoplasm.