Meanwhile, the spatial transcriptome also demonstrated that COL1A1 and SDC1 co‐localized in spatially adjacent COL1A1+ CAFs and breast cancer cells (Figure 6J), particularly the interaction between COL1A1+ CAFs and breast cancer cells was negatively correlated with the distribution of T cells to some extent (Figure 6J), suggesting that COL1A1+ CAFs could hinder the infiltration of T cells into cancer cells. The gene discussed is COL1A1; the disease is breast cancer.