Although several treatment approaches have been shown to improve muscle histopathology in mouse models of LAMA2-CMD (Aoki et al., 2013; Durbeej, 2015; Hagiwara et al., 2006; Qiao et al., 2005), only one clinical trial has been performed for this congenital muscular dystrophy. Here, LAMA2 is linked to congenital muscular dystrophy.