As shown in Fig. (3A), TNF failed to enhance the sEPSC kinetic properties in miR-142-HE striatal slices (decay time and half width: HE-VEH vs. HE-TNF: p >0.05), whereas it induced the expected increase of the duration of the glutamatergic transmission in WT slices relatively to the basal conditions (WT-TNF vs. WT-VEH: decay time p <0.001 and half width p <0.01; WT-TNF vs. HE-VEH: decay time and half width p <0.05), in accordance with the in vivo experiments [13]. This evidence concerns the gene TNF and hereditary elliptocytosis.