Moreover, JAK-STAT signaling has been implicated in SARS-CoV-2-induced inflammation by recruiting macrophages, monocytes, neutrophils, natural killer cells, lymphocytes, and dendritic cells towards the cytokine storm and eventual manifestation of ARDS and even death (Satarker et al., 2021). The gene discussed is SOAT1; the disease is acute respiratory distress syndrome.