CYBB-LINC01140-TLR4, CYBB- LINC01140- SLC38A1, TLR4- LINC01140- SLC38A1, and CTSB- ZFHX4-AS1- CYBB were considered to be potential RNA regulatory pathways involved in the pathogenesis of TAO. The gene discussed is CYBB; the disease is thromboangiitis obliterans.