An increased level of EREG was a risk prognostic factor in the following types of cancer: glioma, adrenocortical carcinoma, kidney renal clear cell carcinoma, cervical cancer, pancreatic adenocarcinoma, Pan-kidney cohort, lung adenocarcinoma, bladder urothelial carcinoma, glioblastoma multiforme, acute lymphoblastic leukemia, lung squamous cell carcinoma, and liver hepatocellular carcinoma (Figure 1A; Supplementary Table 1). Here, EREG is linked to central nervous system cancer.