screened key factors regulating colon tumor growth through a gene library and found that BRD4 (bromodomain and extra terminal BET) protein BRD4 played a regulatory role in colon cancer proliferation, BET inhibitors could be used as tumor growth inhibitors, and CCAT1 could be used as biomarkers of BET inhibitors (148). This evidence concerns the gene DNER and malignant colon neoplasm.