However, although some studies have shown that PADI1 is a poor prognostic factor of artificial cancer in pancreatic cancer and clear renal cell carcinoma and that PADI1 can also participate in the progression of laryngeal squamous cell carcinoma (LSCC), its specific mechanism of action still needs further study (145–147). The gene discussed is PADI1; the disease is laryngeal squamous cell carcinoma.