Five urinary biomarkers (DKK-3, CD163, EGF, PRO-C6, C3M) collected at the time of diagnosis AAV were able to differentiate between patients with better or worse final renal function (favourable and unfavourable prognosis) at the end of follow-up with 88.9% accuracy (ROC 0.961, Figure 4), or 92.6% accuracy with serum creatinine included (Table 7). The gene discussed is DKK3; the disease is anti-neutrophil cytoplasmic antibody-associated vasculitis.