Among them, PPARGC1A was expressed at a lower level in colon cancer, which is consistent with our previous result that PPARGC1A was expressed at a lower level in a high-risk group, whereas GABRD showed the opposite trend of expression to PPARGC1A in these cell lines, and PANX2 exhibited large expression differences between cell lines. The gene discussed is PPARGC1A; the disease is malignant colon neoplasm.