Among them, PPARGC1A was expressed at a lower level in colon cancer, which is consistent with our previous result that PPARGC1A was expressed at a lower level in a high-risk group, whereas GABRD showed the opposite trend of expression to PPARGC1A in these cell lines, and PANX2 exhibited large expression differences between cell lines. Here, GABRD is linked to malignant colon neoplasm.