EGFR and lung carcinoma: To examine whether EGFR mutations exist in healthy lung tissue from people who never develop lung cancer in their lifetime, we profiled 59 healthy lung samples collected at autopsy (median 3 samples per patient, n = 19 patients) from participants in the PEACE study (NCT03004755) who died of other cancers (Supplementary Table 7 and Extended Data Figs. 7 and 8a).