For example, Opa1 is required for cancer angiogenesis [18], is upregulated in Cisplatin resistant lung adenocarcinomas [19], in Venetoclax-resistant acute myeloid leukemia cells [20], and in triple-negative breast cancer (TNBC), the growth of which is curtailed by genetic and pharmacological Opa1 inhibition [21]. This evidence concerns the gene OPA1 and triple-negative breast carcinoma.