CRP and cancer: In multivariable Cox-regression models, both baseline CRP and longitudinal changes in CRP were significantly associated with a 17% and 8% increased risk of developing cancer respectively (HRCRP, 1.17; 95% CI, 1.09 to 1.26 and HRΔCRP, 1.08; 95% CI, 1.01 to 1.15) (Table 3).