AURKB and cancer: Moreover, because Aurora B is overexpressed in highly aneuploid cancers (Pfister et al., 2018; Smith et al., 2005; Takeshita et al., 2013) and its overexpression was recently shown to inhibit Aurora B activity toward different kinetochore substrates (Britigan et al., 2022), it will be important to investigate whether anaphase surveillance and error correction mechanisms are disrupted in human cancers.