Although the increase in apoptosis and decrease in proliferation may also lead to a decrease in the number of migrating and invading cells to a certain extent, a prior study showed that the loss of RPL32 in breast cancer reduces the protein levels of matrix metalloproteinase (MMP)‐2 and MMP‐9, and significantly reduces cell migration and invasion,12 suggesting that RPL32 has the potential to inhibit the migration and invasion of cancer cells by downregulating the expression of MMPs. This evidence concerns the gene MMP2 and cancer.