Analysis of both WT and ΔRD1 infection demonstrated that the loss of monocytes in CCR2-deficient animals caused a significantly increased neutrophil accumulation (Fig. 6A and Fig. S8A) without impacting on bacterial load (Fig. 6F and Fig. S8B), supporting the notion that neutrophil accumulation does not simply reflect the bacterial burden in the tissue (Fig. S1F to H). Here, CCR2 is linked to infection.