Subdivision of the CD64+ compartment into Ly6ChiMHCII− monocytes (gate 1 [G1]), Ly6C+MHCII+ monocytes (G2), Ly6C−MHCII+ monocytes (G3), and Ly6C−MHCIIlow tissue-resident macrophages (G4) showed that infection, within 1 week, caused an increase primarily of G2 monocytes and that G4 macrophage numbers were subsequently reduced compared to baseline (Fig. 1D and E, Fig. S1I, and Fig. S2A to D). This evidence concerns the gene FCGR1A and infection.