Additionally, it has been suggested that CD147 as an entry receptor for SARS-CoV-2 enables the virus to penetrate the infected cell cytoplasm and activate the NLR family pyrin domain containing 3 (NLRP3) inflammasome that cleaves IL-1ß and IL-18 in COVID-19 patients [5, 19, 20]. Here, NLRP3 is linked to COVID-19.