We determined the prognostic value of GNB4 in GC using the publicly accessible Kaplan–Meier plotter online platform and found that patients with GC having a high GNB4 expression exhibited shorter overall survival (OS; P < 0.0001, Fig. 1E) and progression-free survival (P < 0.0001, Fig. 1F). This evidence concerns the gene GNB4 and gastric cancer.