Analysis of serum samples derived from pregnant women with COVID-19 using a different proteomic platform indicated the specific upregulation of IFNL1 and its receptor, IFNLR1, in severe/critical patients compared to mild/moderate or asymptomatic44, which conflicts with earlier findings that IFN responses are delayed and impaired in non-pregnant COVID-19 patients164. This evidence concerns the gene IFNL1 and COVID-19.