TP53 and neoplasm: Immuno-histochemical localization of p53 and Caspase proteins revealed negative reactivity of p53 and Caspase proteins in the muscles of healthy negative control group (G1 group), whereas, weak reactivity for p53 gene and negative reactivity for Caspase gene were observed in the tumor tissues of tumor control group (G2 group) as seen in Figs. 9 and 10.