A possible explanation is that CRP below 23 mg/L, or CRP in the range between 23 and 82 mg/L with an NLR below 9.7, as well as CRP below 40 mg/L (using criteria based on CRP only), are very problematic in terms of predicting infection due to a significant prevalence of infectious inflammation in these groups (Fig. 4). Here, CRP is linked to infection.