Additionally, in some noninfectious "metabolic inflammatory" conditions (such as smoking, uremia, cardiac ischemia) CRP levels can rise to 2–10 mg/L, while mild to moderate disorders (such as an uncomplicated skin infection, urinary tract infection or pneumonia) can raise CRP to 50–100 mg/L within six hours16. The gene discussed is CRP; the disease is myocardial ischemia.