Although there is currently no direct evidence of a regulatory role for m6A in cancer cell transdifferentiation, a series of transdifferentiation-related regulators or signaling pathways such as p53, H19, and mTOR signaling are broadly mediated by m6A regulators, which needs to be further explored to better understand tumor phenotypic plasticity [168, 171, 172]. Here, MTOR is linked to cancer.