COVID + patients had higher levels of syndecan-1, a component of the endothelial glycocalyx, than either non-COVID sepsis patients (Fig. 3I, 812 ± 65 ng/mL vs 283 ± 188 ng/mL, p = 0.0094) or healthy volunteers (812 ± 65 ng/mL vs 65 ± 10 ng/mL, p = 0.03 and 283 ± 188 vs 65 ± 10 ng/mL ng/mL, p = 0.02). Here, SDC1 is linked to Sepsis.