NR2F2 and melanoma: The scaled average expression of these NR2F2-Iso2 signature genes correlated directly (r = 0.55, p < 0.001) with the scaled NR2F2-Iso2 expression (Fig. 4c) and inversely (r = −0.38, p < 0.001) with NR2F2-Iso2 methylation status (Fig. 4d, e) across melanoma patient samples from TCGA.