Regarding paricalcitol, its availability in SUS is aimed at patients with PTHequal to or greater than 500 pg/mL and, for cinacalcet, for patients with PTH levelsabove 800 pg/mL, which may be the first option in the presence of hypercalcemiaand/or hyperphosphatemia and PTH values between 500 and 800 pg/mL6. The gene discussed is PTH; the disease is hyperphosphatemia.