HITT overexpression in 4T1 cells attenuated tumor growth under both conditions (Figure 1, A–C), but it suppressed tumor growth more evidently in the control mice (HITT/vector control: 25%–34%) than in anti-CD8α antibody–treated mice (HITT/vector control: 78%–80%) (Figure 1, A–C). This evidence concerns the gene CD8A and neoplasm.