CLIP1 and glioblastoma: Further interrogation of these clusters revealed that GBM cell lines with high invadopodia matrix-degrading activity (LN229 and MU41) had a greater abundance of proteins involved in invadopodia maturation and proteolytic activity (including BSG, CLIP1, MMP14, MMP2, RAB5A) than the low invadopodia activity cell line, MU4 (Fig. 3B).