The significance of these observations became clear when we tested the effect of LMX1A/LMX1B overexpression during stress-induced cell death in mDANs treated with the mitochondrial poison, rotenone (a complex I inhibitor widely used as a PD-inducing model, e.g., Betarbet et al., 2000). The gene discussed is LMX1A; the disease is Parkinson disease.